DLS measures particle size and particle size distribution in a liquid dispersion. Zeta potential analysis measures the electrical potential around dispersed particles and can provide information about dispersion stability. Zeta potential data can help assess whether nanoparticles are likely to remain dispersed or form agglomerates.
DLS measures particles in a liquid dispersion. A dry powder must therefore be dispersed in a suitable liquid before analysis. The choice of liquid and dispersion conditions is important because dissolution, agglomeration or poor dispersion can affect the measured particle size.
The exact measurement range depends on the material, concentration and measurement conditions. DLS is primarily used for particles in the nanoscale range and can measure nanoparticles down to approximately 3 nanometres. The upper limit is approximately 10 micrometres, although the technique is most suitable for smaller particles in suspension.
DLS measures the hydrodynamic diameter of particles in suspension. This represents how the particles move through the liquid and can include the influence of particle shape, surface coatings, solvation layers and agglomeration.
Dynamic light scattering, or DLS, is a technique used to measure the size distribution of particles dispersed in a liquid. A laser detects fluctuations in the light scattered by particles undergoing Brownian motion, and this information is used to calculate their hydrodynamic particle size.
